Large banana and measuring tape, such as man's large penis.

MANY men know little or nothing about PEYRONIES but suffer from it in varying degrees, in extreme cases embarrassed to strip before a woman. Peyronies is curvature of the penis, which may sometimes be so curved that it presents like a bow from which an arrow can be67 fired, when it becomes erect. So embarrassed can it make a man become that he’d rather push in, limp, and then try to force erection within. Many women may not be able to tolerate the pain of the curvature and may wish to have nothing to do with such a man again. As I said in earlier parts of the series, Peyronies can be worse than erectile dysfunction and low sperm count, either in its effects or therapy. Although some medical researchers say the causes of Peyronies are unknown, others suggest the possibilities;

  1. Trauma
  2. Scar tissue
  3. Aging
  4. Genetic predisposition
  5. Connective tissue disorder

We obtain more information about Peyronies from www.healthline.com:

“The main symptoms of Peyronie’s disease is the formation of flat scar tissue called plaque. This scar tissue can generally be flat through the skin. Plaque normally forms on the upper side of the penis, but may also occur on the bottom or side. Sometimes plaque goes all the way around the penis, causing a “wasting” or “bottleneck” deformity. Plaque may gather calcium and become very hard. Scar tissue may cause painful erection, soft erection or severe curvature. Scar tissue on a certain part of the penis reduces elasticity in that area. Plaque on the top of the penis may cause it to bend upwards during an erection. Plaque on the side may cause curvature towards that side. More than one plaque can cause complex curvatures. Curvature may make sexual penetration more difficult. Scar tissue may cause shrinkage or shortening of the Penis.”

This website suggests that there is no cure for Peyronies’s disease and that, sometimes, it may disappear on its own. But it agrees it may be treatable. In the United States, the Food and Drugs Administration (FDA) approved only one drug for dissolving excessive build-up of collagen, a structural protein which gives body structures their rigid forms. This drugs is injected into the penis. Two other oral drugs are permitted. One is well known for the treatment of high blood pressure. The other breaks down fibrous tissue.

Men challenged with Peyronies’s must wonder if Mother Nature cannot deliver them of it. She can. But there are few scientific studies to back evidence that she does.  In 2001, a study published in BJU Intentional “concluded that Acetyl-L-Carnitine is significantly more effective and safer than Tamoxifen in treating acute and chronic Peyronie’s disease.” Acetyl L- Carnitine, acetylated form of L-Carnitine, is naturally produced in our bodies. These days, it comes as a dietary supplement from the health food store because we produce not enough of it as we age or because our diet does not produce enough of the basic ingredients from which the body makes it. In the body, Acetyl L-Carnitine breaks down to Carnitine which is then used to transport fat from the blood into the mitochondria, energy factories in the cells. It is an amino acid (protein-building block) found in most cells in the body after being produced in the liver and kidney. It is stored in the brain, skeletal muscles and sperm especially. Being an antioxidant in addition to the various roles it performs in the body, Acetyl- L Carnitine is used by Peyronies therapist to protect the penis tissue against the plaque damage and support the healing process. Leading Peyronies physicians who prescribe Acetyl- L-Carnitine give no more than 1000mg two times a day. On the other hand, TAMOXI FEN, a drug sold under the name NOLVADEX, is used for breast cancer therapy in men and women. Another help from Mother Nature may very well be Co-enzyme Q10 (CoQ10), an antioxidant always mentioned in this column for its capacity to energize the entire body, the heart in particular, and, through this, expand the body’s capacity not only to function properly but, also, to deal with all the problems which confront it. According to www.healthline.com:

“Result of a 2010 study published in the International Journal of Impotence Research found that Co-enzyme Q10 supplements improve erectile function. They also reduced penile curvature in patients with early chronic Peyronies’s disease. Another area of interest for researchers is enzyme therapy. Many people say these enzymes, also called proteolytic enzymes, because they digest proteins, do not work as well as they are claimed they do, but there is, also, widespread acclaim for them. The three principal ones among them are: 1.Serrapeptase 2. Nattokinese and 3. Bromelain.

This column mentions them always when it comes to the dissolution of growths, including uterine fibroids. Serrapeptase was discovered in the cocoon of the silkworm. The cocoon is so tough, a lot of force, using a knife, cutlass or even an axe may be required to force it open. But when the silkworm is mature and ready to step into the world, it produces a secretion which melts down this hard shell as though it were ice melting in the tropical sun. Nattokinese melts clots in blood vessels and has proven useful in dissolving blockages in blood vessels which may cause elevated blood pressure (hypertension), strokes and heart attacks. Bromelain, chiefly found in the stem of pineapples, digests denatured and exogenous (foreign) protein.  The website www.the-bent-penis-website.com says:

“Some new therapies of this type are enabling many people to safely and effectively reverse certain conditions and enjoy a more much higher degree of health and wellbeing. Because of this, systemic enzyme therapy (orally taken enzymes that reach the whole body) is now being tested on Peyronies’s disease, a penile bending or curving caused by scar tissue and or fibrous plaque. And even though the chemical tests are proving to be a failure for straightening erection, the products are being sold as if they are the greatest things on earth for Peyronies’s disease. The greatest benefit of this form of treatment in Peyronies’s disease has been shown to be pain relief. The three main items currently being recommended for dissolving fibrous tissue in Peyronies’s disease are;

  1. Serrapeptase
  2. Nattokinese
  3. Bromelain.

These are all natural food substances. They have been used individually and together. “Proteolytic have been shown to be effective in reducing or relieving uterine fibroids, hardening of the arteries, rheumatoid arthritis, fibrocystic breast disease, Carpel tunnel syndrome, and pulmonary fibrosis. These conditions present similar fibrous tissue pathology. In scientific cycles, this is often sufficient clinical justification to use a treatment in related conditions. This is where the problem comes in for Peyronies’s disease sufferers. For pain relief, use of the substances as treatment seem to be as effective as Aspirin, Ibuprofen, other NSADs (non-steroidal anti-inflammatory drugs) as well as steroids. The advantage to this is that they do not have the immuno suppressive and other possible dangerous side effects known to accompany the drugs. Enzymes used for systemic therapy are best taken between meals on an empty stomach. The reason is: They are digestants. They dissolve things. If you take them with meals, they would be mostly used up digesting the food and never make it into the bloodstream. But they should not be taken together with the type of medications mentioned above. They can intensify the strength of these medication and could potentially cause bleeding. In chemical tests, healing and pain relief using enzymes in many related conditions has shown improvement and diminish of pain 100% faster than in the placebo-controlled group.”

PABA

About 10 years ago, PABA food supplement was popular among nutritional health therapies in Nigeria, especially because it was reported good for overcoming gray hair and vitiligo, discoloration of the skin. From www.peyronies-disease-help.com we learn:

“Para-Aminobenzoic acid, or PABA is a non-protein amino acid that is widely distributed in Nature. It can be a wonderful addition to your Peyronies’s disease treatment plan. Many years ago, when B vitamins were first being researched, PABA was referred to as Vitamin BX. We now know it is neither a Vitamin nor an essential vitamin nutrient for humans, since it is made in the body by beneficial bacteria found normally in the small intestine. PABA is used in the body to incorporate protein into living tissue as well as to reverse this process by breaking down protein. It is also used in formation of red blood cells, as well as an intermediary step in the manufacture of Folic acid in the intestine. PABA also assists in maintaining the health of your intestinal flora (the beneficial bacteria found in the intestine). It has been linked to hair growth as well as reversing the graying of hair, but this result seems to be inconclusive, except when there is significant B vitamin deficiency. People suffering from Vitiligo (over-pigmentation of skin) or without Pigment in some spots have reported an improvement of that skin coloration after taking PABA supplementation. Para-Amino Benzoic Acid is also used in sun screen preparations since it can help protect the skin against ultraviolet radiation. Found in liver, kidney, Brewer’s yeast, molasses, whole grains, mushroom and spinach, PABA is also made by intestinal bacteria (FLORA). While most of the research done on Peyronie’s treatment has been conducted with Potassium Para-Amino Benzoate (POTABA), this particular form of PABA frequently causes severe gastric distress, and for this reason it is a prescription medication. The most safe and less expensive PABA could be readily gotten without a prescription, and, hence, it is less expensive without sacrificing effectiveness of treatment.”

How does PABA affect Peyronies’s beneficially? The website reports:

“PABA is reported to have an (anti- scar) effect in the body, and for this reason it is used to treat certain skin conditions in which fibrosis, inelasticity or thickening of the skin occurs. This is the reason PABA is a great Peyronie’s treatment. The reputed anti-fibrotic action of PABA may be done to its stimulation of increased oxygen uptake at the tissue levels, which enhances the oxygen-dependence monoamine oxidase activity that in turn prevents or causes regression of tissue fibrosis. Amino Benzoic Potassium is used medically to treat fibrosis, a condition in which the skin and underlying tissues thicken and become less flexible. This condition occurs in such diseases as Peyronie’s disease, dermatomyositis, morphea, scleroderma, and linear scleroderma.  It is also used to treat non-supporative inflammation that occurs in such disease as dermatomyositis, pemphigus, and again, Peyronie’s disease. It is likely because of the suspected quality of PABA that is reported by many to be effective in treatment of PD. Supporting this idea, from the world literature, we find reports of 2,552 cases treated with POTABA by 1996 that have shown improvement in 60 percent of the cases studied, with a range of improvement from 10 percent to 82 percent depending on the study, and a reported median failure rate of 40 percent. The wide variation of success (10 percent to 82 percent) in the review of the reflection of the wide variance of the PD process, once again confirming this is a very difficult condition to study and determine success rate.”

Low sperm count

There are far too many causes of low sperm count than this space can accommodate. I will address some of them briefly.

  1. Consuming large amounts of sodium benzoate, a preservative in foods, with large amounts of vitamin C (Ascorbic acid) has been shown to damage the testes, affecting hormone and sperm production. At Babcock University in Ilisan, South-western Nigeria, experiments in this area feature regularly in the degree project of anatomy students. (One of such students is Adesina Musa Titilayo). But in moderate amounts both do not appear to damage the testes. It is not advisable to consume large amounts of Vitamin C (Ascorbic acid) without alkalizers. That is why this column often suggests Alkaline Vitamin C. This comes with alkaline buffers such as Magnesium, Manganese, Iron, Selenium e.t.c.
  2. If a pregnant woman has too much of estrogen, a female hormone, and if the coming baby is a male, the excess estrogen may damage the sertoli cells of the foetal testes. These cells help to provide nurture for infant sperm cells. They are nick named “nurse or mother” cells of the testes by some people because of this. If hyper Estrogenation damages their population in the womb, there would be famine among sperm cells in the testes and, through natural selection and survival of the fittest, few sperm cells may survive, leading to low sperm count. Adult men may pick up more estrogen than is safe for their reproductive system from such sources as poultry egg, poultry birds (chickens and turkeys for example) and from cellophane wraps of water (pure water) or food. When cellophane is heated this helps to transfer Xenoestrogen from the cellophane to its contents.
  3. Bacterial, viral and yeast infections may damage and kill sperm cells. If the tubes which deliver them to the penile shaft are infected, the possibility exists that scars may form and inflammation may occur in these tubes, making sperm delivery difficult.
  4. This has to do with drainage problems in the testes. If non-return valves in the veins of the testes become incompetent, back flow of circulation occurs and the vein may become engorged. One way a Varicocele may cause low sperm count is by increasing testicular pressure. The testes cannot stand high temperature, which was why they descended from the body to their present location. Tight clothing affects them because of the high temperature it generates. These days, men wear boxer shorts to prevent over heating of the testes.
  5. Poor diet. The sperm need an alkaline and anti-oxidant rich environment to thrive. The diet and bodies of many men are acid-forming and acidic respectively and the body is riddled with free radicals. A good diet will provide the testes with such food factors as vitamin E, Alpha Lipoic Acid, Zinc, Omega- fish oil. (Walnut, flax seeds, oily fish, chia seeds etc.), Lecithin, folic acid.
  6. Electro pollution. Body cells operate on a certain electromagnetic wave length. Many electrical devices operate on a higher pitch, disrupting the rhythm of the cells. Cell phone kept in trouser pockets may do this. Ditto laptops placed on the lap. Ditto exposure to photocopying machines.
  7. Zinc deficiency. About 80% of the zinc in a man’s body is stored in the prostate gland to provide nurture and anti-oxidant protection for the sperm. Over indulgence in sexual intercourse and frequent ejaculation cause zinc losses in the reproductive system, weak and unhealthy sperm, and low sperm count. That is why zinc food supplement in the diet helps to improve sperm count, especially when L-arginine is taken along with it.

As stated earlier, this space cannot accommodate all the causes of low sperm count. The bodies of many men challenged with low sperm count are toxic and acidic. Such men need to detoxify themselves and alkalize their system. I once met with a young man who drank beer almost all the hours of the day that he was awake. His diet was nothing to write home about. His sperm count was terribly low. The sperm motility was terribly sluggish. The sperm cells gummed together (agglutinated) easily, suggesting there was not enough vitamin E in his testes. And the morphology?   The head of the sperm cell were excessively large and easily detach from the tail whenever the sperm cell try to swim. This man needed Zinc, L-arginine, Lecithin, Vitamin E, Selenium, Grape Seed Extract (GSE), Spirulina and Kale, to mention a few of male reproductive system enhancing food factors.